Week 10 brings another three-team bye. Chicago, Philadelphia, and Tampa Bay are off, which means no Bucky Irving, no Saquon Barkley, and no Caleb Williams this weekend. The other 14 games are still ahead, starting with Washington at the Giants on Thursday night. MyGameSim's NFL Start or Sit tool ranks every position using projected fantasy points from our game simulations.
Here are the top projected players at each spot for Week 10. These numbers come straight from our model, not consensus rankings, so a few of them will look different from what you see elsewhere.
Quarterbacks
Jayden Daniels leads the QB board at 23.4 projected fantasy points at the Giants on Thursday night, so get him locked in early. Tyler Shough is right behind him at 23.3 hosting Carolina, and Dak Prescott (22.5 vs. San Francisco) makes it a strong top three. Drake Maye (21.3 at Detroit) plays in Sunday's early-morning kickoff, so set him before you go to bed Saturday.
Deshaun Watson (21.3 vs. Houston) and Joe Burrow (20.8 vs. Pittsburgh) both clear 20 points. Brock Purdy (20.0 at Dallas) and Josh Allen (19.6 at the Jets) follow, with Geno Smith (19.0 vs. Buffalo) on the other side of that matchup. Drew Lock (18.4 at Las Vegas) rounds out the top ten for the Seahawks. The full QB Start or Sit list is the place to find a bye-week fill-in.
Running Backs
Jahmyr Gibbs is the top running back again at 26.7 projected points at home against New England. Kyren Williams (24.3 at Arizona) and Kenneth Walker III (22.5 at Atlanta) make a clear top three. Jaylen Warren (21.7 at Cincinnati) is the Sunday night name and a strong start if you have him.
Bijan Robinson (20.3 vs. Kansas City) and Chuba Hubbard (19.7 at New Orleans) sit next. James Cook III (18.7 at the Jets) and Jonathan Taylor (18.6 vs. Miami) are still every-week plays. Christian McCaffrey (17.1 at Dallas) and Javonte Williams (16.1 vs. San Francisco) give the Cowboys and 49ers game fantasy juice on both sides. With Irving on bye, the RB projections will help you find a replacement.
Wide Receivers
CeeDee Lamb is the clear WR1 at 23.9 projected points against San Francisco, well ahead of the rest of the position. Jaxon Smith-Njigba (20.3 at Las Vegas) is the only other receiver north of 20. Drake London (16.4 vs. Kansas City) and Chris Olave (16.0 vs. Carolina) round out a strong top four.
Tee Higgins (14.1 vs. Pittsburgh) edges Ja'Marr Chase (13.2) in the same Sunday night game, so both Bengals receivers are startable. Amon-Ra St. Brown (13.9 vs. New England) stays a must-start alongside Gibbs. Malik Nabers (13.1 vs. Washington) is the Thursday option. Matthew Golden (12.6) and Christian Watson (11.0) give Green Bay two names against Minnesota. Every receiver is ranked on the WR Start or Sit page.
Tight Ends
Trey McBride (16.4 vs. the Rams) and Isaiah Likely (16.3 vs. Washington) are nearly tied at the top of the TE board. Likely is the Thursday night play and another reminder that he has become a weekly starter in our sims. George Kittle (12.1 at Dallas) is a clear third.
Hunter Henry (9.4 at Detroit) and Travis Kelce (9.4 at Atlanta) are bunched next. Harold Fannin Jr. (9.1 vs. Houston), Tyler Higbee (9.1 at Arizona), and Brock Bowers (8.9 vs. Seattle) fill out the TE1 group. Dalton Schultz and Brenton Strange are the streaming options just behind them. The full TE Start or Sit rankings go deeper.
Kickers and Defense
Tyler Bass leads kickers at 11.5 projected points at the Jets, followed by Jason Myers (11.4 at Las Vegas) and Evan McPherson (10.4 vs. Pittsburgh). Jake Bates (10.3 vs. New England) and Chris Boswell (9.9 at Cincinnati) are next. On defense, Cleveland is the top play at 16.0 points against Houston, with Minnesota (14.0 at Green Bay) and Indianapolis (13.0 vs. Miami) right behind. New Orleans and Detroit both project for 12.0. If you stream defenses, the Browns and Colts are the best looks.
Need help with a flex spot? The FLEX board puts running backs, receivers, and tight ends on one list so you can compare them directly.
Games to Watch
Thursday's Commanders and Giants game has Daniels, Nabers, and Likely all near the top of their positions, so set those lineups early. New England and Detroit open Sunday with an early-morning kickoff, which puts Maye, Gibbs, St. Brown, Henry, and Bates on the clock Saturday night. San Francisco at Dallas is the best afternoon fantasy game, with Prescott, Lamb, Purdy, McCaffrey, Kittle, and Javonte Williams all in play. Sunday night's Steelers and Bengals matchup features Burrow, Warren, Higgins, Chase, McPherson, and Boswell. Monday night's Chargers and Ravens game is quieter in our offensive projections, so treat it as more of a streaming week for Baltimore and Los Angeles skill players.
How to use this
Our Start or Sit grades combine projected fantasy points with opposing defensive strength from the same simulations. Players with higher projections and softer matchups rise to the top. That does not mean you should bench a proven star for every surprise name, but when the model and your gut disagree, take a second look.
Free users can see the top of each position list. GameSim+ unlocks the full Week 10 Start or Sit board, plus detailed player projections for every game on the slate. Good luck this week.
