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Illinois
| Player | Injury | Status | Details |
|---|---|---|---|
| Alex Perry | Shoulder | Out | |
| BJ Thurman | Foot | Out | |
| Daniel Brown | Undisclosed | Out | |
| Grant Smith | Undisclosed | Out | |
| Jacob Eberhart | Undisclosed | Questionable | |
| Jacob Harvey | Undisclosed | Questionable | |
| Jayshon Platt | Undisclosed | Questionable | |
| John Forster | Knee | Questionable | |
| Kenyon Alston | Undisclosed | Questionable | |
| Tanner Hollinger | Undisclosed | Out | |
| Will Vala | Undisclosed | Questionable |
Indiana
| Player | Injury | Status | Details |
|---|---|---|---|
| Kellan Wyatt | Undisclosed | Questionable |
Maryland
| Player | Injury | Status | Details |
|---|---|---|---|
| Sean Williams | Undisclosed | Questionable | |
| Zahir Mathis | Leg | Out |
Michigan
| Player | Injury | Status | Details |
|---|---|---|---|
| Andrew Babalola | Undisclosed | Out | |
| Devon Baxter | Undisclosed | Questionable | |
| Donovan Johnson | Undisclosed | Questionable | |
| Micah Ka'apana | Undisclosed | Out |
Michigan State
| Player | Injury | Status | Details |
|---|---|---|---|
| Rai'shawn Elmore | Suspension | Out |
Minnesota
| Player | Injury | Status | Details |
|---|---|---|---|
| Luke Drzewiecki | Not Injury Related | Questionable | |
| Zeke Bates | Undisclosed | Questionable |
Nebraska
| Player | Injury | Status | Details |
|---|---|---|---|
| Demitrius Bell | Knee | Questionable | |
| Larry Miles | Foot | Out |
Northwestern
| Player | Injury | Status | Details |
|---|---|---|---|
| Braden Blueitt | Undisclosed | Questionable | |
| Chris Petrucci | Undisclosed | Questionable | |
| Yannis Karlaftis | Undisclosed | Questionable |
Ohio State
| Player | Injury | Status | Details |
|---|---|---|---|
| Kyle Parker | Undisclosed | Out |
Oregon
| Player | Injury | Status | Details |
|---|---|---|---|
| Dillon Gresham | Neck | Doubtful | |
| Kingston Lopa | Undisclosed | Questionable |
Penn State
| Player | Injury | Status | Details |
|---|---|---|---|
| Andrew Rappleyea | Undisclosed | Questionable | |
| Brian Kortovich | Undisclosed | Questionable | |
| Cooper Alexander | Undisclosed | Questionable | |
| D'Antae Sheffey | Undisclosed | Questionable | |
| Gabe Burkle | Knee | Doubtful |
Purdue
| Player | Injury | Status | Details |
|---|---|---|---|
| Kylan Fox | Knee | Out |
Rutgers
| Player | Injury | Status | Details |
|---|---|---|---|
| Famah Toure | Knee | Questionable |
UCLA
| Player | Injury | Status | Details |
|---|---|---|---|
| Aidan Mizell | Undisclosed | Questionable | |
| Jonah Smith | Undisclosed | Questionable | |
| Ty Dieffenbach | Undisclosed | Questionable |
USC
| Player | Injury | Status | Details |
|---|---|---|---|
| Elijah Newby | Undisclosed | Out | |
| Jahkeem Stewart | Foot | Out | |
| Kilian O'Connor | Leg | Out | |
| Roderick Tezeno | Foot | Questionable | |
| Romero Ison | Undisclosed | Questionable | |
| Sam Huard | Undisclosed | Questionable | |
| Terrell Anderson | Undisclosed | Out |
Washington
| Player | Injury | Status | Details |
|---|---|---|---|
| CJ Christian | Achilles | Out | |
| Jordan Washington | Neck | Doubtful | |
| Landen Hatchett | Undisclosed | Out |
Wisconsin
| Player | Injury | Status | Details |
|---|---|---|---|
| Bryan Jackson | Undisclosed | Questionable | |
| Emerson Mandell | Undisclosed | Questionable | |
| Eugene Hilton | Undisclosed | Probable | |
| Gideon Ituka | Undisclosed | Out | |
| Jaylon Domingeaux | Undisclosed | Questionable | |
| Julius Pope | Undisclosed | Questionable | |
| Kevin Heywood | Undisclosed | Questionable |
